VCU rebounded from their loss to George Washington on Tuesday and beat Duquesne 80-65.
Richmond won their A-10 home opener over Dayton 73-64.
George Mason remained winless in the Atlantic-10 after losing at Rhode Island in overtime 71-69.
Virginia beat Florida St 78-66 for their first season sweep of the Seminoles since 2001.
William and Mary beat James Madison 78-65.
Randolph-Macon won their seventh in a row, 60-53 over Randolph.