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STUDY: “Harmless” virus could treat acne

Posted at 6:38 PM, Sep 25, 2012
and last updated 2012-09-25 18:38:26-04

(CBS News) Could the secret to keeping acne at bay be a virus?

 Scientists at UCLA and the University of Pittsburgh have discovered that “phages”, which are 11 types of harmless viruses that live on our skin, has the natural ability to infect and kill the acne-causing bacteriaPropionibacterium acnes. They hope their discovery could lead to new acne treatments and other medical advances.

 “There are two fairly obvious potential directions that could exploit this kind of research,” study co-author Graham Hatfull, Eberly Family Professor of Biotechnology at the University of Pittsburgh, said in the press release. “The first is the possibility of using the phages directly as a therapy for acne. The second is the opportunity to use phage-derived components for their activities.”

Acne affects 40 to 50 million Americans and is the most common skin disorder, according to The American Academy of Dermatology. About 85 percent of people will have acne at some point in their lives, and by mid-teens, 40 percent of people will have acne or acne scarring.

 Acne is caused when hair follicles become clogged with oil and dead skin cells, and then gets infected with Propionibacterium acnes bacteria and becomes inflamed, according the Mayo Clinic. Although the bacterium regularly occurs on human skin, it increases during puberty, leading to more acne outbreaks.

 For the study, scientists isolated and found the genetic sequence for the phages andPropionibacterium acnes from human volunteers with and without acne. They discovered that the phages make a protein called endolysin, which breaks down the bacteria before killing it.

Read more at CBS news.